Bibliometric Analysis of Medicinal Plants from Brunei Darussalam: Uncovering Novel Anticancer Targets Tropical Journal of Natural Product Research
Article Sidebar
Main Article Content
Abstract
Brunei Darussalam boasts a rich biodiversity of medicinal plants, including species like Piper betel, Piper sarmentosum, Piper crocatum, and agarwood, which have demonstrated anticancer properties in previous studies. This bibliometric analysis aimed to explore research trends related to these plants and anticancer activity. A Scopus database search conducted on July 27th, 2024, yielded 210 relevant articles using the keywords "Piper betel" OR "Piper sarmentosum" OR "Piper crocatum" OR "Agarwood" AND "Cancer." VOSviewer was employed for data analysis and visualization. Results indicate a strong association between oral cancer and the four target plants, with agarwood being the second most frequently connected keyword. Notably, research collaboration between these two areas remains limited, suggesting a potential research gap. While East Asian researchers, particularly from Chung Shan Medical University in Taiwan, have been at the forefront of this field, the absence of research originating from Brunei Darussalam presents a significant opportunity for local investigation. Cancer Letters (Elsevier), which has published ten relevant articles, emerges as a potential target journal for future research in this domain. This bibliometric analysis provides valuable insights into research trends and potential avenues for future investigations into the anticancer properties of these Bruneian medicinal plants.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
How to Cite
References
Holdsworth D. Traditional Medicinal Plants of Brunei Darussalam Part I. Bukit Udal. Int J Pharmacogn. 1991; 29(4):245-250. https://doi.org/10.3109/13880209109082889
Mohiddin MYBH, Chin W, Holdsworth D. Traditional Medicinal Plants of Brunei Darussalam Part II Sengkurong. Int J Pharmacogn. 1991; 29(4):252-258. https://doi.org/10.3109/13880209109082891
Mohiddin MYBH, Chin W, Holdsworth D. Traditional Medicinal Plants of Brunei Darussalam Part III. Sengkurong. Int J Pharmacogn. 1992; 30(2):105-108. https://doi.org/10.3109/13880209209053967
Biswas P, Anand U, Saha SC, Kant N, Mishra T, Masih H, Bar A, Pandey DK, Jha NK, Majumder M, Das N, Gadekar VS, Shekhawat MS, Kumar M, Radha, Proćków J, de la Lastra JMP, Dey A. Betelvine (Piper betle L.): A comprehensive insight into its ethnopharmacology, phytochemistry, and pharmacological, biomedical and therapeutic attributes. J Cell Mol Med. 2022; 26(11):3083-3119. https://doi.org/10.1111/jcmm.17323
Sun X, Chen W, Dai W, Xin H, Rahmand K, Wang Y, Zhang J, Zhang S, Xu L, Han T. Piper sarmentosum Roxb.: A review on its botany, traditional uses, phytochemistry, and pharmacological activities. J Ethnopharmacol. 2020; 263:112897. https://doi.org/10.1016/j.jep.2020.112897
Gong Y, Li HX, Guo RH, Widowati W, Kim YH, Yang SY, Kim YR. Anti-allergic Inflammatory Components from the Leaves of Piper crocatum Ruiz & Pav. Biol Pharm Bull. 2021; 44(2):245-250. https://doi.org/10.1248/bpb.b20-00726
Gogoi R, Sarma N, Begum T, Chanda SK, Lekhak H, Sastry GH, Lal M. Agarwood (Aquilaria malaccensis L.) a quality fragrant and medicinally significant plant based essential oil with pharmacological potentials and genotoxicity. Ind Crops Prod. 2023; 197:116535. https://doi.org/10.1016/j.indcrop.2023.116535
Debela DT, Muzazu SG, Heraro KD, Ndalama MT, Mesele BW, Haile DC, Kitui SK, Manyazewal T. New approaches and procedures for cancer treatment: Current perspectives. SAGE Open Med. 2021; 9:20503121211034366. https://doi.org/10.1177/20503121211034366
Yuan H, Ma Q, Ye L, Piao G. The Traditional Medicine and Modern Medicine from Natural Products. Molecules. 2016; 21(5):559. https://doi.org/10.3390/molecules21050559
Pratama MRF, Praditapuspa EN, Widiyana AP, Kesuma D, Poerwono H, Widiandani T, Rudyanto M, Siswodihardjo S. Bibliometric Analysis of Research on Boesenbergia rotunda, Pinostrobin, and Their Derivatives: Dominance of Southeast Asian Researchers. Rev Cub Inf Cienc Salud. 2023; 34:e2423.
Poerwono H, Rudyanto M. Bibliometric Study of Microwave-Assisted Synthesis of Flavanone Derivatives. Borneo J Pharm. 2023; 6(4):339–348. https://doi.org/10.33084/bjop.v6i4.5602
Bramer WM, de Jonge GB, Rethlefsen ML, Mast F, Kleijnen J. A systematic approach to searching: an efficient and complete method to develop literature searches. J Med Libr Assoc. 2018; 106(4):531-541. https://doi.org/10.5195/jmla.2018.283
Burnham JF. Scopus database: a review. Biomed Digit Lib. 2006; 3:1. https://doi.org/10.1186/1742-5581-3-1
Ward MH, deKok TM, Levallois P, Brender J, Gulis G, Nolan BT, VanDerslice J, International Society for Environmental Epidemiology. Workgroup report: Drinking-water nitrate and health--recent findings and research needs. Environ Health Perspect. 2005; 113(11):1607-1614. https://doi.org/10.1289/ehp.8043
Dai C, Chen Q, Wan T, Liu F, Gong Y, Wang Q. Literary runaway: Increasingly more references cited per academic research article from 1980 to 2019. PloS One. 2021; 16(8):e0255849. https://doi.org/10.1371/journal.pone.0255849
Li YC, Cheng AJ, Le LY, Huang YC, Chang JTC. Multifaceted Mechanisms of Areca Nuts in Oral Carcinogenesis: The Molecular Pathology from Precancerous Condition to Malignant Transformation. J Cancer. 2019; 10(17):4054-4062. https://doi.org/10.7150/jca.29765
Jeng JH, Chang MC, Hahn LJ. Role of areca nut in betel quid-associated chemical carcinogenesis: current awareness and future perspectives. Oral Oncol. 2001; 37(6):477-492. https://doi.org/10.1016/s1368-8375(01)00003-3
Kudva AK, Rao S, Rao P, Periera R, Bhandari G, Mathew JM, Ashwini K, Pais MLJ, Swamy MK, Baliga MS. Piper betle Linn. in Cancer: Past, Present, and Future. In: Akhtar M, Swamy M, editors. Anticancer plants: Properties and Application. Springer: Singapore; 2018. pp. 327-347.
https://doi.org/10.1007/978-981-10-8548-2_14
Sari LM, Wulandari D, Bustami A, Subita GP, Auerkari EI. Tannin Screening, Phenolic Compounds Analysis, and Antiproliferative Activity of Areca Nut Extract by Decreasing Ki-67 Protein in Oral Squamous Carcinoma Cell Lines. Trop J Nat Prod Res. 2020; 4(9):563-570. https://doi.org/10.26538/tjnpr/v4i9.12
Usman S, Jamal A, Teh MT, Waseem A. Major Molecular Signaling Pathways in Oral Cancer Associated with Therapeutic Resistance. Front Oral Health. 2021; 1:603160. https://doi.org/10.3389/froh.2020.603160
Zhang N, Xue S, Song J, Zhou X, Zhou D, Liu X, Hong Z, Xu D. Effects of various artificial agarwood-induction techniques on the metabolome of Aquilaria sinensis. BMC Plant Biol. 2021; 21(1):591. https://doi.org/10.1186/s12870-021-03378-8
Wang S, Yu Z, Wang C, Wu C, Guo P, Wei J. Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants. Molecules. 2018; 23(2):342. https://doi.org/10.3390/molecules23020342
Buddhan R, Manoharan S, Elanchezhiyan C, Muralinaidu R, Karthik M. Myrtenal Modulates the Immunoexpression of Cell Proliferative, Angiogenic and Invasive Markers in DMBA-Induced Hamster Oral Carcinogenesis. Trop J Nat Prod Res. 2020; 4(9):550-557. https://doi.org/10.26538/tjnpr/v4i9.10
Wilder EI, Walters WH. Using Conventional Bibliographic Databases for Social Science Research: Web of Science and Scopus are not the Only Options. Sch Assess Rep. 2021; 3(1):4. http://dx.doi.org/10.29024/sar.36
Lee HC, Yin PH, Yu TN, Chang YD, Hsu WC, Kao SY, Chi CW, Liu TY, Wei YH. Accumulation of mitochondrial DNA deletions in human oral tissues -- effects of betel quid chewing and oral cancer. Mutat Res. 2001; 493(1-2):67-74. https://doi.org/10.1016/s1383-5718(01)00160-7
Liao G, Mei WL, Dong WH, Li W, Wang P, Kong FD, Gai CJ, Song XQ, Dai HF. 2-(2-Phenylethyl)chromone derivatives in artificial agarwood from Aquilaria sinensis. Fitoterapia. 2016; 110:38-43. https://doi.org/10.1016/j.fitote.2016.01.011
Wu SJ, Chen YJ, Shieh TY, Chen CM, Wang YY, Lee KT, Lin YM, Chien PH, Chen PH. Association study between novel CYP26 polymorphisms and the risk of betel quid-related malignant oral disorders. Sci World J. 2015; 2015:160185. https://doi.org/10.1155/2015/160185
Tsou HH, Ko HT, Chen CT, Wang TW, Lee CH, Liu TY, Wang HT. Betel quid containing safrole enhances metabolic activation of tobacco specific 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Environ Pollut. 2019; 251:13-21. https://doi.org/10.1016/j.envpol.2019.04.080
Mullins CH, Boyd CJ, Lindeman B. Factors Associated with the Highest and Lowest Cited Research Articles in General Surgery Journals. J Surg Res. 2020; 250:39-44. https://doi.org/10.1016/j.jss.2019.12.014
Sharma M, Sarin A, Gupta P, Sachdeva S, Desai AV. Journal impact factor: its use, significance and limitations. World J Nucl Med. 2014; 13(2):146. https://doi.org/10.4103/1450-1147.139151
Chen L, Chen H, Cai C, Yuan J, Gai C, Liu S, Mei W, Dai H. Seven new 2-(2-phenethyl)chromone derivatives from agarwood of Aquilaria walla. Fitoterapia. 2023; 165:105421. https://doi.org/10.1016/j.fitote.2022.105421
Yeung AWK, Heinrich M, Kijjoa A, Tzvetkov NT, Atanasov AG. The ethnopharmacological literature: An analysis of the scientific landscape. J Ethnopharmacol. 2020; 250:112414. https://doi.org/10.1016/j.jep.2019.112414
Kifli N, Wint Z, Jaini NH, Hamid MA, Linda YYL. Prevalence on the Use of Traditional Medicine in Brunei Darussalam. J Homeopath Ayurvedic Med. 2014; 3(155):2167. http://dx.doi.org/10.4172/2167-1206.1000155
Aarons GA, Seijo C, Green AE, Moullin JC, Hasson H, Schwarz UVT, James S, Ehrhart MG, Ducarroz S, Sevdalis N, Willging C. Fostering international collaboration in implementation science and research: a concept mapping exploratory study. BMC Res Notes. 2019; 12(1):778.